2'-O-Methylcytidine-d3, CAS 2653209-08-4

Product Description: 2'-O-Methylcytidine-d3 is deuterium labeled 2'-O-Methylcytidine (HY-W011834). 2'-O-Methylcytidine is a 2'-substituted nucleoside as a inhibitor of HCV replication. 2'-O-Methylcytidine inhibits RNA-dependent RNA polymerase (NS5B)-catalyzed RNA synthesis in vitro, in a manner that is competitive with substrate nucleoside triphosphate.

Applications: COVID-19-anti-virus

Formula: C10H12D3N3O5

References: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216./[2]Steven S Carroll, et al. Inhibition of hepatitis C virus RNA replication by 2'-modified nucleoside analogs. J Biol Chem. 2003 Apr 4;278(14):11979-84

CAS Number: 2653209-08-4

Molecular Weight: 260.26

Research Area: Infection

Solubility: 10 mM in DMSO

Target: HCV;Isotope-Labeled Compounds

• SKU: MEXHY-W011834S-1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-W011834S-1
• Package Unit: 1 mg
• Quantity Unit: STK