3-O-Methyltolcapone-d7

Product Description: 3-O-Methyltolcapone-d7 is a deuterium labeled 3-O-Methyltolcapone. 3-O-Methyltolcapone is a metabolite of Tolcapone. Tolcapone is an orally active, reversible, selective and potent COMT inhibitor. Tolcapone crosses the blood-brain barrier, and can be used for treatment of Parkinson's disease[1][2].

Applications: Neuroscience-Neurodegeneration

Formula: C15H6D7NO5

References: [1]Jorga K, et al. Metabolism and excretion of tolcapone, a novel inhibitor of catechol-O-methyltransferase. Br J Clin Pharmacol. 1999 Oct;48(4):513-20./[2]Ceravolo R, et al. 18F-dopa PET evidence that tolcapone acts as a central COMT inhibitor in Parkinson's disease. Synapse. 2002 Mar 1;43(3):201-7.

Molecular Weight: 294.31

Compound Purity: 99.0

Research Area: Neurological Disease

Solubility: 10 mM in DMSO

Target: COMT

• SKU: MEXHY-100642S-100UG
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-100642S-100UG
• Package Unit: 100 μg
• Quantity Unit: STK