7-Methylguanosine-d3

Product Description: 7-Methylguanosine-d3 is the deuterium labeled 7-Methylguanosine[1]. 7-Methylguanosine is a novel cNIIIB nucleotidase inhibitor with IC50 value of 87.8 ± 7.5 μM[2].

Applications: COVID-19-anti-virus

Formula: C11H13D3N5O5

References: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216./[2]Kozarski M, et al. 7-Methylguanosine monophosphate analogues with 5'-(1,2,3-triazoyl) moiety: Synthesis and evaluation as the inhibitors of cNIIIB nucleotidase. Bioorg Med Chem. 2018 Jan 1;26(1):191-199.

Molecular Weight: 301.29

Compound Purity: 98.54

Research Area: Inflammation/Immunology

Solubility: 10 mM in DMSO/H2O : 25mg/mL (ultrasonic;warming;heat to 60°C)

Target: Endogenous Metabolite;Nucleoside Antimetabolite/Analog

• SKU: MEXHY-122524S-5
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-122524S-5
• Package Unit: 5 mg
• Quantity Unit: STK