Product Description: Adenine-d is the deuterium labeled Adenine. Adenine (6-Aminopurine), a purine, is one of the four nucleobases in the nucleic acid of DNA. Adenine acts as a chemical component of DNA and RNA. Adenine also plays an important role in biochemistry involved in cellular respiration, the form of both ATP and the cofactors (NAD and FAD), and protein synthesis[1][2][3].
Formula: C5H4DN5
References: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. ;ORO J, et al. Synthesis of purines under possible primitive earth conditions. I. Adenine from hydrogen cyanide. Arch Biochem Biophys. 1961 Aug;94:217-27.;Griffiths AJF, et al. An Introduction to Genetic Analysis. 7th edition. New York: W. H. Freeman; 2000. Structure of DNA.;Reader V. The assay of vitamin B(4). Biochem J. 1930;24(6):1827-31.
CAS Number: 109923-52-6
Molecular Weight: 136.13
Compound Purity: 99.90
Research Area: Cancer
Solubility: 1 M HCl : 20mg/mL (ultrasonic)/DMSO : ≥ 10mg/mL/H2O : 2mg/mL (ultrasonic;warming;heat to 60°C)
Target: DNA/RNA Synthesis;Endogenous Metabolite
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