Product Description: AICAR-13C2,15N (Acadesine-13C2,15N; AICA Riboside-13C2,15N) is the 13C and 15N labeled AICAR (HY-13417)[1]. AICAR (Acadesine) is an adenosine analog and a AMPK activator. AICAR regulates the glucose and lipid metabolism, and inhibits proinflammatory cytokines and iNOS production. AICAR is also an autophagy, YAP and mitophagy inhibitor[2][3].
Formula: C7 13C2H14N3 15NO5
References: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.
CAS Number: 1609374-70-0
Molecular Weight: 261.21
Research Area: Others
Solubility: 10 mM in DMSO
Target: AMPK;Autophagy;Endogenous Metabolite;Isotope-Labeled Compounds;Mitophagy;YAP