Amantadine-d15, CAS 33830-10-3

Product Description: Amantadine-d15 is the deuterium labeled Amantadine. Amantadine (1-Adamantanamine) is an antiviral agent with activity against influenza A viruses. Amantadine blocks the proton flow through the M2 ion channel (M2 proton channel of influenza A) and thus prevents the release of viral RNA into the cytoplasm of the infected cells. Amantadine is an antiparkinsonian agent[1][2].

Formula: C10H2D15N

References: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. /[2]Suzuki H, et al. Emergence of amantadine-resistant influenza A viruses: epidemiological study. J Infect Chemother. 2003;9(3):195-200./[3]Hubsher G, et al. Amantadine: the journey from fighting flu to treating Parkinson disease. Neurology. 2012;78(14):1096-1099.

CAS Number: 33830-10-3

Molecular Weight: 166.34

Compound Purity: 98.0

Research Area: Cancer; Infection; Neurological Disease

Solubility: 10 mM in DMSO/DMSO : 10mg/mL (ultrasonic;adjust pH to 2 with 1M HCl)

Target: Apoptosis;Influenza Virus;Orthopoxvirus;SARS-CoV

• SKU: MEXHY-B0402S-10
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-B0402S-10
• Package Unit: 10 mg
• Quantity Unit: STK