Aminobenzenesulfonic auristatin E-d8

Product Description: Aminobenzenesulfonic auristatin E-d8 is the deuterium labeled Aminobenzenesulfonic auristatin E. Aminobenzenesulfonic auristatin E is a drug-linker conjugate for ADC. Aminobenzenesulfonic auristatin E has potent antitumor activity by using Auristatin E (a cytotoxic tubulin modifier), linked via the ADC linker Aminobenzenesulfonic[1][2].

Applications: Cancer-programmed cell death

Formula: C37H56D8N6O8S

References: [1]Kevin HAMBLETT, et al. Anti-her2 biparatopic antibody-drug conjugates and methods of use. Patent WO2019173911A1. /[2]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-223.

Molecular Weight: 761.05

Compound Purity: 98.02

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: Drug-Linker Conjugates for ADC;Microtubule/Tubulin

• SKU: MEXHY-145989S-1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-145989S-1
• Package Unit: 1 mg
• Quantity Unit: STK