Product Description: Antitumor agent-183 (compound 3f) has antitumor activity with metabolic stability. Antitumor agent-183 inhibits cancer cell growth, with IC50s less than 5 nM for A549, HCT116, and HS578T cells. The albumin-bound nanoparticle formulation of Antitumor agent-183 has prolonged retention in the tumor tissues[1].
Applications: Cancer-programmed cell death
Formula: C31H18D15BrN4O9
References: [1]Yu W, et al. Deuterium Editing of Small Molecules: A Case Study on Antitumor Activity of 1,4-Benzodiazepine-2,5-dione Derivatives. J Med Chem. 2024 Jul 18.
CAS Number: 2775428-94-7
Molecular Weight: 700.61
Research Area: Cancer
Target: Cytochrome P450