AZ-5104-d2, CAS 2719691-01-5

Product Description: AZ-5104-d2 is the deuterium labeled AZ-5104. AZ-5104 is an EGFR inhibitor with IC50s of 1 nM, 6 nM, 1 nM, 25 nM and 7 nM for EGFRL858R/T790M, EGFRL858R, EGFRL861Q, EGFR and ErbB4, respectively[1].

Applications: Cancer-Kinase/protease

Formula: C27H29D2N7O2

References: [1]Cross DA, et al. AZD9291, an irreversible EGFR TKI, overcomes T790M-mediated resistance to EGFR inhibitors in lung cancer. Cancer Discov. 2014 Sep;4(9):1046-61.

CAS Number: 2719691-01-5

Molecular Weight: 487.59

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: EGFR

• SKU: MEXHY-B0793S1-1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-B0793S1-1
• Package Unit: 1 mg
• Quantity Unit: STK