Benztropine-d3 (mesylate), CAS 202529-16-6

Product Description: Benztropine-d3 (mesylate) is the deuterium labeled Benztropine mesylate[1]. Benztropine mesylate (Benzatropine mesylate) is an orally active centrally acting anticholinergic agent that can be used for Parkinson's disease research. Benztropine mesylate is an anti-histamine agent and a dopamine re-uptake inhibitor. Benztropine mesylate is also a human D2 dopamine receptor allosteric antagonist. Benztropine mesylate also has anti-CSCs (cancer stem cells) effects[2][3].

Applications: COVID-19-immunoregulation

Formula: C22H26D3NO4S

References: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216./[2]Santosh S Kulkarni, et al. Comparative structure-activity relationships of benztropine analogues at the dopamine transporter and histamine H(1) receptors. Bioorg Med Chem. 2006 Jun 1;14(11):3625-34./[3]Jihong Cui, et al. New use of an old drug: inhibition of breast cancer stem cells by benztropine mesylate. Oncotarget. 2017 Jan 38(1):1007-1022.

CAS Number: 202529-16-6

Molecular Weight: 406.55

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: Dopamine Receptor;Histamine Receptor;mAChR

• SKU: MEXHY-B0520AS1-1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-B0520AS1-1
• Package Unit: 1 mg
• Quantity Unit: STK