Product Description: BTK-IN-26 (compound 18) is a potent inhibitor of Bruton's tyrosine kinase (BTK) and its C481 mutant, with IC50 values of 0.7 and 0.8 nM for BTK and BTK C481S, respectively. BTK-IN-26 can be used for cancer and autoimmune diseases research[1].
Applications: COVID-19-immunoregulation
Formula: C27H26D3FN6O3
References: [1]Xiangyang Chen, et al. Heterocyclic compounds as btk inhibitors. Patent, WO2022037649A1.
CAS Number: 2762043-61-6
Molecular Weight: 507.57
Research Area: Cancer; Inflammation/Immunology
Solubility: 10 mM in DMSO
Target: Btk