Cetrorelix-d10

Product Description: Cetrorelix-d10 (SB-75-d10) is deuterium labeled Cetrorelix. Cetrorelix is a potent gonadotrophin-releasing hormone (GnRH) antagonist. Cetrorelix inhibits the endogenous luteinizing hormone surge during ovarian stimulation. Cetrorelix reduces cyclophosphamide induced ovarian follicular destruction in mice[1][2].

Applications: Metabolism-protein/nucleotide metabolism

Formula: C70H82D10ClN17O14

References: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216./[2]Diedrich K, et al. Suppression of the endogenous luteinizing hormone surge by the gonadotrophin-releasing hormone antagonist Cetrorelix during ovarian stimulation. Hum Reprod. 1994 May;9(5):788-91. /[3]Meirow D, et al. The GnRH antagonist cetrorelix reduces cyclophosphamide-induced ovarian follicular destruction in mice. Hum Reprod. 2004 Jun;19(6):1294-9.

Molecular Weight: 1441.10

Research Area: Endocrinology

Target: GnRH Receptor;Isotope-Labeled Compounds

• SKU: MEXHY-P0009S1-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-P0009S1-0
• Package Unit: Get quote
• Quantity Unit: STK