Product Description: Cholestenone-d7 is deuterium labeled Cholestenone. Cholestenone (4-Cholesten-3-one), the intermediate oxidation product of cholesterol, is metabolized primarily in the liver. Cholestenone is highly mobile in membranes and influences cholesterol flip-flop
Applications: Metabolism-protein/nucleotide metabolism
Formula: C27H37D7O
References: [1]Rosenheim O, et al. The mechanism of coprosterol formation in vivo: 1. Cholestenone as an intermediate. Biochem J. 1943 Oct;37(4):513-4./[2]Neuvonen M, et, al. Enzymatic oxidation of cholesterol: properties and functional effects of cholestenone in cell membranes. PLoS One. 2014 Aug 26;9(8):e103743./[3]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-223.
CAS Number: 2389048-48-8
Molecular Weight: 391.68
Research Area: Metabolic Disease
Solubility: 10 mM in DMSO
Target: Endogenous Metabolite;Isotope-Labeled Compounds
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