Dapagliflozin-13C6-1

Product Description: Dapagliflozin-13C6-1 is 13C labeled Dapagliflozin. Dapagliflozin (BMS-512148), a new type of agent used to treat diabetes mellitus (DM), is a competitive sodium/glucose cotransporter 2 (SGLT2) inhibitor, which results in excretion of glucose into the urine[1]. Dapagliflozin induces HIF1 expression and attenuates renal IR injury[2].

Applications: Metabolism-sugar/lipid metabolism

Formula: C15 13C6H25ClO6

References: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216./[2]Pelissier T, et al. The orofacial capsaicin test in rats: effects of different capsaicin concentrations and morphine. Pain. 2002 Mar;96(1-2):81-7.

Molecular Weight: 414.83

Research Area: Metabolic Disease;Cancer

Target: Isotope-Labeled Compounds;SGLT

• SKU: MEXHY-10450S5-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-10450S5-0
• Package Unit: Get quote
• Quantity Unit: STK