Darolutamide-d4, CAS 2484757-20-0

Product Description: Darolutamide-d4 (ODM-201-d4) is deuterium labeled Darolutamide. Darolutamide (ODM-201;BAY-1841788) is a potent androgen receptor (AR) antagonist with an IC50 of 26 nM in in vitro assay[1].

Formula: C19H15D4ClN6O2

References: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216./[2]Moilanen AM, et al. Discovery of ODM-201, a new-generation androgen receptor inhibitor targeting resistance mechanisms toandrogen signaling-directed prostate cancer therapies. Sci Rep. 2015 Jul 3;5:12007. doi: 10.1038/srep12007.

CAS Number: 2484757-20-0

Molecular Weight: 402.87

Research Area: Cancer

Target: Androgen Receptor;Isotope-Labeled Compounds

• SKU: MEXHY-16985S-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-16985S-0
• Package Unit: Get quote
• Quantity Unit: STK