Dibenzothiophene-d8, CAS 33262-29-2

Product Description: Dibenzothiophene-d8 is the deuterium labeled Dibenzothiophene (HY-B0973). Dibenzothiophene is an orally active and a noncompetitive CYP1A inhibitor. Dibenzothiophene inhibits CYP1A-mediated EROD activity with Km of 0.592 μM. Dibenzothiophene interacts with the AHR pathway. Dibenzothiophene enhances the embryotoxicity of β-naphthoflavone (HY-114740). Dibenzothiophene shows acute toxicity in mice. Dibenzothiophene is mainly used for the study of the mechanism of developmental toxicity in organisms[1][2].

Formula: C12D8S

References: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.

CAS Number: 33262-29-2

Molecular Weight: 192.31

Research Area: Metabolic Disease

Solubility: 10 mM in DMSO

Target: Aryl Hydrocarbon Receptor;Cytochrome P450;Isotope-Labeled Compounds

• SKU: MEXHY-B0973S-5
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-B0973S-5
• Package Unit: 5 mg
• Quantity Unit: STK