DM4-d6

Product Description: DM4-d6 is deuterium labeled DM4. DM4 is is an antitubulin agent that inhibit cell division. DM4 can be used in the preparation of antibody agent conjugate.

Applications: Cancer-programmed cell death

Formula: C38H48D6ClN3O10S

References: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216./[2]Tang R, et al. P-gp activity is a critical resistance factor against AVE9633 and DM4 cytotoxicity in leukaemia cell lines, but not a major mechanism of chemoresistance in cells from acute myeloid leukaemia patients. BMC Cancer. 2009 Jun 23;9:199.

Molecular Weight: 786.40

Compound Purity: 99.11

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: ADC Cytotoxin;Isotope-Labeled Compounds;Microtubule/Tubulin

• SKU: MEXHY-12454S-100UG
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-12454S-100UG
• Package Unit: 100 μg
• Quantity Unit: STK