eCF506-d5

Product Description: eCF506-d5 is deuterated labeled eCF506 (HY-112096). eCF506 is a highly potent and orally bioavailable inhibitor of the non-receptor tyrosine kinase Src with an IC50 of less than 0.5 nM.

Applications: Cancer-Kinase/protease

Formula: C26H33D5N8O3

References: [1]Fraser C, et al. Rapid Discovery and Structure-Activity Relationships of Pyrazolopyrimidines That Potently Suppress Breast Cancer Cell Growth via SRC Kinase Inhibition with Exceptional Selectivity over ABL Kinase. J Med Chem. 2016 May 26;59(10):4697-710./[2]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.

Molecular Weight: 515.66

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: Isotope-Labeled Compounds;Src

• SKU: MEXHY-112096S-1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-112096S-1
• Package Unit: 1 mg
• Quantity Unit: STK