Elacestrant-d4-1

Product Description: Elacestrant-d4-1 is the deuterium labeled Elacestrant (HY-19822). Elacestrant is an orally available and selective estrogen receptor degrader (SERD) with IC50s of 48 and 870 nM for ERα and ERβ, respectively[1][2].

Applications: Cancer-programmed cell death

Formula: C30H34D4N2O2

References: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216./[2]Garner F, et al. RAD1901: a novel, orally bioavailable selective estrogen receptor degrader that demonstrates antitumor activity in breast cancer xenograft models. Anticancer Drugs. 2015 Oct;26(9):948-56.

Molecular Weight: 462.66

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: Estrogen Receptor/ERR;Isotope-Labeled Compounds

• SKU: MEXHY-19822S1-1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-19822S1-1
• Package Unit: 1 mg
• Quantity Unit: STK