Product Description: Erlotinib-13C6 is a 13C-labeled Erlotinib. Erlotinib is a directly acting EGFR tyrosine kinase inhibitor, with an IC50 of 2 nM for human EGFR[1].
Applications: Cancer-Kinase/protease
Formula: C16 13C6H23N3O4
References: [1]Moyer JD, et al. Induction of apoptosis and cell cycle arrest by CP-358,774, an inhibitor of epidermal growth factor receptor tyrosine kinase. Cancer Res. 1997, 57(21), 4838-4848./[2]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.
CAS Number: 1211107-68-4
Molecular Weight: 399.39
Research Area: Cancer
Solubility: 10 mM in DMSO
Target: Autophagy;EGFR;Isotope-Labeled Compounds