Product Description: Erlotinib-d6 (hydrochloride) a deuterium labeled Erlotinib Hydrochloride. Erlotinib Hydrochloride inhibits purified EGFR kinase with an IC50 of 2 nM[1]. Erlotinib-d6 (hydrochloride) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
Applications: Cancer-Kinase/protease
Formula: C22H18D6ClN3O4
References: [1]Moyer JD, et al. Induction of apoptosis and cell cycle arrest by CP-358,774, an inhibitor of epidermal growth factor receptor tyrosine kinase. Cancer Res. 1997 Nov 1;57(21):4838-48.
CAS Number: 1189953-78-3
Molecular Weight: 435.93
Compound Purity: 98.13
Research Area: Cancer
Solubility: 10 mM in DMSO/H2O : ≥ 0.1mg/mL
Target: Autophagy;EGFR