Erlotinib-d8, CAS 1266656-97-6

Product Description: Erlotinib-d8 (CP-358774-d8) is deuterium labeled Erlotinib. Erlotinib (CP-358774) is a directly acting EGFR tyrosine kinase inhibitor, with an IC50 of 2 nM for human EGFR. Erlotinib reduces EGFR autophosphorylation in intact tumor cells with an IC50 of 20 nM. Erlotinib is used for the treatment of non-small cell lung cancer[1]. Erlotinib is a click chemistry reagent, itcontains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

Applications: Cancer-programmed cell death

Formula: C22H15D8N3O4

References: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

CAS Number: 1266656-97-6

Molecular Weight: 401.49

Research Area: Cancer

Target: Isotope-Labeled Compounds

• SKU: MEXHY-50896S3-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-50896S3-0
• Package Unit: Get quote
• Quantity Unit: STK