Product Description: Fidaxomicin-d7 (OPT-80-D7) is the deuterium labeled Fidaxomicin. Fidaxomicin (OPT-80), a macrocyclic RNA polymerase inhibitor, has a narrow spectrum of activity. Fidaxomicin selectively eradicates pathogenic Clostridium difficile with minimal disruption to the multiple species of bacteria that make up the normal, healthy intestinal flora[1][2].
Applications: COVID-19-immunoregulation
Formula: C52H67D7Cl2O18
References: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216./[2]Poxton IR, et al. Fidaxomicin: a new macrocyclic, RNA polymerase-inhibiting antibiotic for the treatment of Clostridium difficile infections. Future Microbiol. 2010 Apr;5(4):539-48.
CAS Number: 2143934-06-7
Molecular Weight: 1065.08
Compound Purity: 97.18
Research Area: Infection
Solubility: 10 mM in DMSO
Target: Antibiotic;Apoptosis;Bacterial;Isotope-Labeled Compounds