Product Description: HSD17B13-IN-56-D3 (Compound 169) is an inhibitor of hydroxysteroid 17β-dehydrogenase 13 (HSD17B13) with an IC50 value of ≤ 0.1 μM for estradiol. HSD17B13-IN-56-D3 can be used for research on liver diseases, metabolic diseases, or cardiovascular diseases, such as NAFLD or NASH, as well as drug-induced liver injury (DILI)[1].
Applications: Metabolism-protein/nucleotide metabolism
Formula: C25H15D3Cl2F3N3O4
References: [1]Anandan S K, et al. Dichlorophenol HSD17B13 inhibitors and uses thereof. U.S., WO2022103960. 2023-11-28.
CAS Number: 2770247-60-2
Molecular Weight: 555.35
Research Area: Metabolic Disease
Solubility: 10 mM in DMSO
Target: 17β-HSD