Product Description: Ketotifen-d3 (fumarate) is the deuterium labeled Ketotifen fumarate. Ketotifen (HC 20511) fumarate is a second-generation noncompetitive H1-antihistamine and mast cell stabilizer, which is used to prevent asthma attacks[1][2].
Applications: Metabolism-protein/nucleotide metabolism
Formula: C23H20D3NO5S
References: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216./[2]Klooker TK, et al. The mast cell stabiliser ketotifen decreases visceral hypersensitivity and improves intestinal symptoms in patients with irritable bowel syndrome. Gut. 2010 Sep;59(9):1213-21./[3]Zhang H, et al. Advances in the discovery of exosome inhibitors in cancer. J Enzyme Inhib Med Chem. 2020;35(1):1322-1330.
CAS Number: 1795138-23-6
Molecular Weight: 428.52
Compound Purity: 99.23
Research Area: Inflammation/Immunology; Endocrinology
Solubility: DMSO : 50 mg/mL (ultrasonic)
Target: Histamine Receptor;Influenza Virus;SARS-CoV
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