Product Description: L-Glutamic acid-13C2 is the 13C labeled L-Glutamic acid[1]. L-Glutamic acid acts as an excitatory transmitter and an agonist at all subtypes of glutamate receptors (metabotropic, kainate, NMDA, and AMPA). L-Glutamic acid shows a direct activating effect on the release of DA from dopaminergic terminals[2].
Applications: Neuroscience-Neurodegeneration
Formula: C3 13C2H9NO4
References: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216./[2]Giorguieff MF, et al. Presynaptic effect of L-glutamic acid on the release of dopamine in rat striatal slices. Neurosci Lett. 1977 Oct;6(1):73-7.
CAS Number: 115473-56-8
Molecular Weight: 149.11
Research Area: Neurological Disease
Solubility: 10 mM in DMSO
Target: Apoptosis;Endogenous Metabolite;Ferroptosis;iGluR
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