Lamivudine-13C,15N2,d2

Lamivudine-13C,15N2,d2
SKU
MEXHY-B0250S1-1
Packaging Unit
1 mg
Manufacturer
MedChemExpress

Availability: loading...
Price is loading...
Product Description: Lamivudine-13C,15N2,d2 (BCH-189-13C,15N2,d2) is a 13C, 15N, and deuterium labeled Lamivudine (HY-B0250). Lamivudine is an orally active and blood-brain barrier permeable nucleoside reverse transcriptase inhibitor (NRTI). Lamivudine inhibits HIV reverse transcriptase 1 and 2 and hepatitis B virus (HBV) reverse transcriptase[1][2][3][4].

Applications: COVID-19-anti-virus

Formula: C7 13CH9D2N 15N2O3S

References: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216./[2]Colledge D, et al. Synergistic inhibition of hepadnaviral replication by lamivudine in combination with penciclovir in vitro. Hepatology. 1997 Jul;26(1):216-25. /[3]Olaniyan LW, et al. Lamivudine-Induced Liver Injury. Open Access Maced J Med Sci. 2015 Dec 15;3(4):545-50. /[4]Mdanda S, et al. Zidovudine and Lamivudine as Potential Agents to Combat HIV-Associated Neurocognitive Disorder. Assay Drug Dev Technol. 2019 Oct;17(7):322-329. 

Molecular Weight: 234.25

Research Area: Infection

Solubility: 10 mM in DMSO

Target: HBV;HIV;Isotope-Labeled Compounds;Reverse Transcriptase
More Information
SKU MEXHY-B0250S1-1
Manufacturer MedChemExpress
Manufacturer SKU HY-B0250S1-1
Package Unit 1 mg
Quantity Unit STK
Product information (PDF) Download
MSDS (PDF)
×