Product Description: Lansoprazole sulfone-13C6 (AG-1813-13C6) is 13C labeled Lansoprazole sulfone. Lansoprazole sulfone (AG-1813) is an orally active and selective inhibitor of H+, K+-ATPase. Lansoprazole sulfone can significantly stimulates gastric acid secretion by inhibiting H+, K+-ATPase. Lansoprazole sulfone has potential applications in duodenal ulcer, gastric ulcer, gastroesophageal reflux disease and Zolinger Ellison disease[1][2].
Applications: Metabolism-protein/nucleotide metabolism
Formula: C10 13C6H14F3N3O3S
References: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216./[2]Swamy G, et al. Crystal structure of lansoprazole sulfone[J]. Journal of Structural Chemistry, 2007, 48: 715-718./[3]Karol MD, et al. Lansoprazole pharmacokinetics in subjects with various degrees of kidney function. Clin Pharmacol Ther. 1997 Apr;61(4):450-8.
CAS Number: 1261398-50-8
Molecular Weight: 391.32
Research Area: Metabolic Disease
Target: Drug Metabolite;Isotope-Labeled Compounds;Proton Pump
English
Deutsch
