Product Description: Liothyronine-13C6-1 is a 13C-labeled Liothyronine. Liothyronine is a potent thyroid hormone receptors TRα and TRβ agonist with Kis of 2.33 nM for hTRα and hTRβ, respectively[1][2].
Applications: Metabolism-protein/nucleotide metabolism
Formula: C9 13C6H12I3NO4
References: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. /[2]Lin KH, et al. Stimulation of proliferation by 3,3',5-triiodo-L-thyronine in poorly differentiated human hepatocarcinoma cells overexpressing beta 1 thyroid hormone receptor. Cancer Lett. 1994 Oct 14;85(2):189-94.
CAS Number: 1213431-76-5
Molecular Weight: 656.93
Compound Purity: 98.06
Research Area: Cancer; Endocrinology
Solubility: 10 mM in DMSO
Target: Thyroid Hormone Receptor