Liproxstatin-1-15N

Product Description: Liproxstatin-1-15N is the 15N labled Liproxstatin-1 (HY-12726). Liproxstatin-1 is a potent ferroptosis inhibitor and inhibits ferroptotic cell death (IC50=22 nM)[1].

Applications: Cancer-programmed cell death

Formula: C19H21ClN3 15N

References: [1]Friedmann Angeli JP, et al. Inactivation of the ferroptosis regulator Gpx4 triggers acute renal failure in mice. Nat Cell Biol. 2014 Dec;16(12):1180-91./[2]Zilka O, et al. On the Mechanism of Cytoprotection by Ferrostatin-1 and Liproxstatin-1 and the Role of Lipid Peroxidation in Ferroptotic Cell Death. ACS Cent Sci. 2017 Mar 22;3(3):232-243/[3]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.

Molecular Weight: 341.84

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: Isotope-Labeled Compounds

• SKU: MEXHY-12726S1-1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-12726S1-1
• Package Unit: 1 mg
• Quantity Unit: STK