Losartan-d2, CAS 1030936-22-1

Product Description: Losartan-d2 is the deuterium labeled Losartan[1]. Losartan is an angiotensin II receptor antagonist, competing with the binding of angiotensin II to AT1 receptors with IC50 of 20 nM.

Applications: Neuroscience-Neuromodulation

Formula: C22H21D2ClN6O

References: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216./[2]Burnier, M. Angiotensin II type 1 receptor blockers. Circulation, 2001. 103(6): p. 904-12.;Ashry, O., et al. Evidence for expression and function of angiotensin II receptor type 1 in pulmonary epithelial cells. Respir Physiol Neurobiol, 2014.

CAS Number: 1030936-22-1

Molecular Weight: 424.92

Research Area: Others

Solubility: 10 mM in DMSO

Target: Angiotensin Receptor

• SKU: MEXHY-17512S3-1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-17512S3-1
• Package Unit: 1 mg
• Quantity Unit: STK