MAT2A-IN-22, CAS 2925330-18-1

Product Description: MAT2A-IN-22 (Compound 29-1) is a BBB-penetrable and orally active MAT2A inhibitor with an IC50 of 4 nM. MAT2A-IN-22 shows selectivity and inhibitory activity against MTAP-deficient cancer cell lines. MAT2A-IN-22 has anti-tumor effects[1].

Applications: Cancer-programmed cell death

Formula: C18H11D3F3N3O

References: [1]Yang S, et al. Discovery of Novel Spirocyclic MAT2A Inhibitors Demonstrating High In Vivo Efficacy in MTAP-Null Xenograft Models. J Med Chem. 2025 Feb 13;68(3):3480-3494.

CAS Number: 2925330-18-1

Molecular Weight: 348.34

Research Area: Cancer

Target: Isotope-Labeled Compounds;Methionine Adenosyltransferase (MAT)

• SKU: MEXHY-170905S-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-170905S-0
• Package Unit: Get quote
• Quantity Unit: STK