Mexiletine-d3

Product Description: Mexiletine-d3 (KOE-1173-d3) is deuterium labeled Mexiletine. Mexiletine is an orally effective antiarrhythmic agent which has also been found to be effective for myotonia and neuropathic pain. Mexiletine exerts its efficacy through blocking sodium channels (IC50 : 75±8 μM for tonic block, 23.6±2.8 μM for use-dependent block), therefore can be used for cardiovascular and neurological research[1][2][3][4][5].

Applications: Neuroscience-Neuromodulation

Formula: C11H14D3NO

References: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

Molecular Weight: 182.28

Research Area: Neurological Disease;Cardiovascular Disease

Target: Isotope-Labeled Compounds

• SKU: MEXHY-119521S-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-119521S-0
• Package Unit: Get quote
• Quantity Unit: STK