Moclobemide-d4

Product Description: Moclobemide-d4 is deuterium labeled Moclobemide. Moclobemide (Ro111163) is a brain-penetrant and reversible monoamine oxidase (MAO-A) inhibitor with an IC50 of 6.061 μM for hMAO-A[1].Moclobemide up-regulates proliferation of hippocampal progenitor cells in chronically stressed mice.

Applications: Neuroscience-Neuromodulation

Formula: C13H13D4ClN2O2

References: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216./[2]Nafiz Öncü Can, et al. Synthesis of New Hydrazone Derivatives for MAO Enzymes Inhibitory Activity. Molecules. 2017 Aug 20;22(8):1381./[3]Yun-feng Li, et al. Moclobemide up-regulates proliferation of hippocampal progenitor cells in chronically stressed mice. Acta Pharmacol Sin. 2004 Nov;25(11):1408-12.

Molecular Weight: 272.76

Compound Purity: 99.0

Research Area: Neurological Disease

Solubility: 10 mM in DMSO/DMSO : 100mg/mL (ultrasonic)

Target: Monoamine Oxidase

• SKU: MEXHY-B0534S1-100UG
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-B0534S1-100UG
• Package Unit: 100 μg
• Quantity Unit: STK