Product Description: Moxonidine-d3 (BDF5895-d3) is deuterium labeled Moxonidine. Moxonidine (BDF5895) is an imidazoline type 1 receptor (I1-R) selective agonist and antihypertensive agent.
Applications: Neuroscience-Neuromodulation
Formula: C9H9D3ClN5O
References: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216./[2]Schafer, U., et al., Presynaptic effects of moxonidine in isolated buffer perfused rat hearts: role of imidazoline-1 receptors and alpha2-adrenoceptors. J Pharmacol Exp Ther, 2002. 303(3): p. 1163-70./[3]Chan, C.K., et al., Imidazoline receptors associated with noradrenergic terminals in the rostral ventrolateral medulla mediate the hypotensive responses of moxonidine but not clonidine. Neuroscience, 2005. 132(4): p. 991-1007.
Molecular Weight: 244.70
Research Area: Neurological Disease;Cardiovascular Disease
Target: Imidazoline Receptor;Isotope-Labeled Compounds
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