N-Desethyl amodiaquine-d5 (dihydrochloride), CAS 1216894-33-5

Product Description: N-Desethyl amodiaquine-d5 (dihydrochloride) is the deuterium labeled N-Desethyl amodiaquine dihydrochloride. N-Desethyl amodiaquine dihydrochloride is the major biologically active metabolite of Amodiaquine. N-Desethyl amodiaquine dihydrochloride is an antiparasitic agent. IC50 values for strains V1/S and 3D7 are 97 nM and 25 nM, respectively[1].

Applications: COVID-19-immunoregulation

Formula: C18H15D5Cl3N3O

References: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216./[2]Sasi P, et al. In vivo and in vitro efficacy of amodiaquine against Plasmodium falciparum in an area of continued use of 4-aminoquinolines in East Africa. J Infect Dis. 2009 Jun 1;199(11):1575-82.

CAS Number: 1216894-33-5

Molecular Weight: 405.76

Compound Purity: 98.76

Research Area: Infection

Solubility: H2O : 100 mg/mL (ultrasonic;warming)

Target: Isotope-Labeled Compounds;Parasite

• SKU: MEXHY-128554S1-5
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-128554S1-5
• Package Unit: 5 mg
• Quantity Unit: STK