N-Methyl-dosimertinib-d5, CAS 2719690-98-7

Product Description: N-Methyl-dosimertinib-d5 is the deuterium labeled of Dosimertinib (HY-142283). Dosimertinib is a highly potent, selective, and orally active deuterated EGFR inhibiotor. Dosimertinib can be used for the research of non-small-cell lung cancer[1][2].

Applications: Cancer-Kinase/protease

Formula: C24H19D5N6O2

References: [1]Yonggang Meng, et al. Discovery of Dosimertinib, a Highly Potent, Selective, and Orally Efficacious Deuterated EGFR Targeting Clinical Candidate for the Treatment of Non-Small-Cell Lung Cancer. J Med Chem. 2021 Jan 28;64(2):925-937. /[2]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-223.

CAS Number: 2719690-98-7

Molecular Weight: 433.52

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: EGFR

• SKU: MEXHY-142283CS-1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-142283CS-1
• Package Unit: 1 mg
• Quantity Unit: STK