Namodenoson-d5

Product Description: Namodenoson-d5 (CF-102-d5) is deuterium labeled Namodenoson. Namodenoson (CF-102) is a selective A3 adenosine receptor (A3AR) agonist (Ki=0.33 nM). Namodenoson displays 2500- and 1400-fold selectivity over A1 and A2A receptors respectively[1][2].

Applications: Cancer-programmed cell death

Formula: C28H44D5NO6S

References: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216./[2]Van Schaick EA et al. Hemodynamic effects and histamine release elicited by the selective adenosine A3 receptor agonist 2-Cl-IB-MECA in conscious rats. Eur J Pharmacol. 1996 Jul 25;308(3):311-4./[3]Jacobson KA et al. Adenosine A3 receptors: novel ligands and paradoxical effects. Trends Pharmacol Sci. 1998 May;19(5):184-91.

Molecular Weight: 532.79

Research Area: Cancer

Target: Adenosine Receptor;Isotope-Labeled Compounds

• SKU: MEXHY-12365S2-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-12365S2-0
• Package Unit: Get quote
• Quantity Unit: STK