Nifurtimox-d4

Product Description: Nifurtimox-d4 is deuterium labeled Nifurtimox. Nifurtimox, an antiprotozoal agent, which is generally used for the treatment of infections with Trypanosoma cruzi, has been used in the therapy of neuroblastoma. Nifurtimox affects enzyme activity of lactate dehydrogenase (LDH).

Applications: COVID-19-immunoregulation

Formula: C10H9D4N3O5S

References: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216./[2]Cabanillas Stanchi KM, et al. Nifurtimox reduces N-Myc expression and aerobic glycolysis in neuroblastoma. Cancer Biol Ther. 2015;16(9):1353-63.

Molecular Weight: 291.32

Research Area: Cancer; Infection

Solubility: 10 mM in DMSO

Target: Isotope-Labeled Compounds;Lactate Dehydrogenase;Parasite

• SKU: MEXHY-W040073S-5
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-W040073S-5
• Package Unit: 5 mg
• Quantity Unit: STK