O-Desmethyltramadol-d6 (hydrochloride), CAS 1261393-87-6

Product Description: O-Desmethyltramadol-d6 (hydrochloride) is a deuterated labeled O-Desmethyltramadol (hydrochloride)[1]. O-Desmethyltramadol (hydrochloride) is a primary active metabolite of Tramadol. O-Demethyltramadol is mainly responsible for its μ-opioid receptor-related analgesic effect. Tramadol is metabolized to O-Demethyltramadol mainly by the cytochrome P450 (CYP) 2D6 enzyme[2].

Formula: C15H18D6ClNO2

References: [1]Lee J, et al. Population pharmacokinetic analysis of tramadol and O-desmethyltramadol with genetic polymorphism of CYP2D6. Drug Des Devel Ther. 2019;13:1751-1761. /[2]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.

CAS Number: 1261393-87-6

Molecular Weight: 291.85

Research Area: Neurological Disease

Target: Drug Metabolite;Isotope-Labeled Compounds

• SKU: MEXHY-109054AS-1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-109054AS-1
• Package Unit: 1 mg
• Quantity Unit: STK