Product Description: Oxaceprol-d3 (N-Acetyl-L-hydroxyproline-d3) is deuterium labeled Oxaceprol. Oxaceprol (N-Acetyl-L-hydroxyproline), an orally active derivative of L-proline, possesses distinct anti-inflammatory activity. Oxaceprol is usually used for the research of osteoarthritis and rheumatoid arthritis[1][2][3].
Formula: C7H8D3NO4
References: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216./[2]Ionac M et al. Oxaceprol, an atypical inhibitor of inflammation and joint damage. Pharmacol Res, 1996 Jun, 33(6):367-73./[3]Harpreet Singh Pawar, et al. Comparative evaluation of therapeutic efficacy of intra-articular oxaceprol with conventional modalities in osteoarthritis animal model. Clin Rheumatol. 2018 Aug;37(8):2195-2201./[4]M Ionac, et al. Oxaceprol, an atypical inhibitor of inflammation and joint damage. Pharmacol Res. 1996 Jun;33(6):367-73./[5]M J Parnham, et al. Antirheumatic agents and leukocyte recruitment. New light on the mechanism of action of oxaceprol. Biochem Pharmacol. 1999 Jul 15;58(2):209-15.
Molecular Weight: 176.19
Research Area: Inflammation/Immunology
Target: Amino Acid Derivatives;Isotope-Labeled Compounds
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