Product Description: Paclitaxel-d5 is a deuterium-labeled Paclitaxel. Paclitaxel is a naturally occurring antineoplastic agent and stabilizes tubulin polymerization[1].
Applications: Cancer-programmed cell death
Formula: C47H46D5NO14
References: [1]Choi YH, et al. Paclitaxel-induced growth arrest and apoptosis is associated with the upregulation of the Cdk inhibitor, p21WAF1/CIP1, in human breast cancer cells. Oncol Rep. 2012 Dec;28(6):2163-9./[2]Dziadyk JM, et al. Paclitaxel-induced apoptosis may occur without a prior G2/M-phase arrest. Anticancer Res. 2004 Jan-Feb;24(1):27-36.
CAS Number: 1129540-33-5
Molecular Weight: 858.94
Compound Purity: 98.0
Research Area: Cancer
Solubility: 10 mM in DMSO/DMF : ≥ 5mg/mL/DMSO : ≥ 5mg/mL/Ethanol : ≥ 1.5mg/mL
Target: ADC Cytotoxin;Isotope-Labeled Compounds;Microtubule/Tubulin