Phenacetin-13C, CAS 72156-72-0

Phenacetin-13C, CAS 72156-72-0
SKU
MEXHY-B0476S1-1
Packaging Unit
1 mg
Manufacturer
MedChemExpress

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Product Description: Phenacetin-13C is the 13C labeled Phenacetin[1]. Phenacetin (Acetophenetidin) is a non-opioid analgesic/antipyretic agent. Phenacetin is a selective COX-3 inhibitor. Phenacetin is used as probe of cytochrome P450 enzymes CYP1A2 in human liver microsomes and in rats[2][3][4].

Applications: COVID-19-immunoregulation

Formula: C9 13CH13NO2

References: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216./[2]Chandrasekharan NV, et al. COX-3, a cyclooxygenase-1 variant inhibited by acetaminophen and other analgesic/antipyretic drugs: cloning, structure, and expression. Proc Natl Acad Sci U S A. 2002 Oct 15;99(21):13926-31./[3]Xiao-Meng He, et al. Effects of long-term smoking on the activity and mRNA expression of CYP isozymes in rats. J Thorac Dis. 2015 Oct 7(10): 1725–1731./[4]Na Gao, et al. Inhibition of Baicalin on Metabolism of Phenacetin, a Probe of CYP1A2, in Human Liver Microsomes and in Rats. PLoS One. 2014 9(2): e89752.

CAS Number: 72156-72-0

Molecular Weight: 180.21

Research Area: Inflammation/Immunology

Solubility: 10 mM in DMSO

Target: COX
More Information
SKU MEXHY-B0476S1-1
Manufacturer MedChemExpress
Manufacturer SKU HY-B0476S1-1
Package Unit 1 mg
Quantity Unit STK
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