PRMT5-MTA-IN-3-d3, CAS 3052146-54-7

Product Description: PRMT5-MTA-IN-3-d3 (compound P22) is the deuterium labeled PRMT5-MTA-IN-3 (HY-172733). PRMT5-MTA-IN-3-d3 is an orally active PRMT5-MTA inhibitor. PRMT5-MTA-IN-3-d3 has antiproliferative effects on HTC116-MTAP del and wild type colorectal cancer HCT-116 cell lines, with IC50 values of 6 nM and 961 nM, respectively. PRMT5-MTA-IN-3-d3 has anticancer effects, especially for MTAP-deficient tumors, such as non-small cell lung cancer (NSCLC), pancreatic cancer[1].

Applications: Cancer-programmed cell death

Formula: C19H14D3F3N6O3

References: [1]Bing Liu, et al. Inhibiteur de prmt5-mta. WO2024152973A1.

CAS Number: 3052146-54-7

Molecular Weight: 437.39

Research Area: Cancer

Target: Histone Methyltransferase;Isotope-Labeled Compounds

• SKU: MEXHY-172733S-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-172733S-0
• Package Unit: Get quote
• Quantity Unit: STK