Product Description: Psychosine-d5 is deuterium labeled Psychosine. Psychosine, a substrate of the galactocerebrosidase (GALC) enzyme, is a potential biomarker for Krabbe disease. Psychosine is a highly cytotoxic lipid, capable of inducing cell death in a wide variety of cell.
Applications: Cancer-Kinase/protease
Formula: C24H42D5NO7
References: [1]M L Escolar, et al. Psychosine, a marker of Krabbe phenotype and treatment effect. Mol Genet Metab. 2017 Jul;121(3):271-278./[2]Jacqueline A Hawkins-Salsbury,et al.Psychosine, the cytotoxic sphingolipid that accumulates in globoid cell leukodystrophy, alters membrane architecture. J Lipid Res.2013 Dec;54(12):3303-11./[3]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-223.
CAS Number: 2260670-12-8
Molecular Weight: 466.66
Compound Purity: 99.0
Research Area: Cancer; Neurological Disease
Solubility: 10 mM in DMSO
Target: PKC
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