(R)-Verapamil-d7 (hydrochloride)

Product Description: (R)-Verapamil-d7 (hydrochloride) is a deuterium labeled (R)-Verapamil hydrochloride. (R)-Verapamil hydrochloride ((R)-(+)-Verapamil hydrochloride) is a P-Glycoprotein inhibitor. (R)-Verapamil hydrochloride blocks MRP1 mediated transport, resulting in chemosensitization of MRP1-overexpressing cells to anticancer agents[1][2].

Applications: Cancer-programmed cell death

Formula: C27H32D7ClN2O4

References: [1]Plumb JA, et al. The activity of verapamil as a resistance modifier in vitro in drug resistant human tumour cell lines is not stereospecific. Biochem Pharmacol. 1990 Feb 15;39(4):787-92./[2]Perrotton T, et al. (R)- and (S)-verapamil differentially modulate the multidrug-resistant protein MRP1. J Biol Chem. 2007 Oct 26;282(43):31542-8. Epub 2007 Jul 22.

Molecular Weight: 498.11

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: Apoptosis;Isotope-Labeled Compounds;P-glycoprotein

• SKU: MEXHY-135336S-1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-135336S-1
• Package Unit: 1 mg
• Quantity Unit: STK