(rac)-Nebivolol-d4, CAS 1219407-55-2

Product Description: (rac)-Nebivolol-d4 is a labelled racemic Nebivolol. Nebivolol selectively inhibits β1-adrenergic receptor with IC50 of 0.8 nM[1][2][3].

Applications: Metabolism-protein/nucleotide metabolism

Formula: C22H21D4F2NO4

References: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216./[2]Brehm BR, et al. Effects of nebivolol on proliferation and apoptosis of human coronary artery smooth muscle and endothelial cells. Cardiovasc Res. 2001 Feb 1;49(2):430-9./[3]Mercanoglu G, et al. The effects of nebivolol on apoptosis in a rat infarct model. Circ J. 2008 Apr;72(4):660-70.

CAS Number: 1219407-55-2

Molecular Weight: 409.46

Research Area: Cardiovascular Disease; Endocrinology

Solubility: 10 mM in DMSO

Target: Adrenergic Receptor

• SKU: MEXHY-B0203BS1-1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-B0203BS1-1
• Package Unit: 1 mg
• Quantity Unit: STK