Raloxifene-d10-1, CAS 2512224-37-0

Product Description: Raloxifene-d10-1 is the deuterium labeled Raloxifene[1]. Raloxifene (Keoxifene) is a benzothiophene-derived selective estrogen receptor modulator (SERM). Raloxifene has estrogen-agonistic effects on bone and lipids and estrogen-antagonistic effects on the breast and uterus. Raloxifene is used for breast cancer and osteoporosis research[2].

Applications: Cancer-programmed cell death

Formula: C28H17D10NO4S

References: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216./[2]Khovidhunkit W, et al. Clinical effects of raloxifene hydrochloride in women. Ann Intern Med. 1999;130(5):431-439./[3]Xu H, et al. Effect of caffeine on ovariectomy-induced osteoporosis in rats. Biomed Pharmacother. 2019112:108650.

CAS Number: 2512224-37-0

Molecular Weight: 483.64

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: Estrogen Receptor/ERR

• SKU: MEXHY-13738S4-1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-13738S4-1
• Package Unit: 1 mg
• Quantity Unit: STK