Riluzole-13C6

Product Description: Riluzole-13C6 (PK 26124-13C6) is 13C labeled Riluzole. Riluzole is an anticonvulsant agent and belongs to the family of use-dependent Na+ channel blocker which can also inhibit GABA uptake with an IC50 of 43 μM.

Applications: Cancer-programmed cell death

Formula: C2 13C6H2F3N2OS

References: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216./[2]He Y, et al. Neuroprotective agent riluzole potentiates postsynaptic GABA(A) receptor function. Neuropharmacology. 2002 Feb;42(2):199-209./[3]Thompson JM, et al. Small-conductance calcium-activated potassium (SK) channels in the amygdala mediate pain-inhibiting effects of clinically available riluzole in a rat model of arthritis pain. Mol Pain. 2015 Aug 28;11:51.

Molecular Weight: 237.13

Research Area: Neurological Disease;Cancer

Target: GABA Receptor;Isotope-Labeled Compounds;Sodium Channel

• SKU: MEXHY-B0211S1-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-B0211S1-0
• Package Unit: Get quote
• Quantity Unit: STK