Product Description: Rimeporide-15N3 (hydrochloride) (EMD-87580-15N3 (hydrochloride)) is 15N labeled Rimeporide hydrochloride. Rimeporide hydrochloride (EMD-87580 hydrochloride) is a potent and selective inhibitor of the Na+/H+ exchanger (NHE-1).
Applications: Metabolism-protein/nucleotide metabolism
Formula: C11H16Cl 15N3O5S2
References: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216./[2]F.Porte-Thomé, et al. Development of Rimeporide, a sodium-hydrogen exchanger (NHE-1) inhibitor, for patients with Duchenne muscular dystrophy. Neuromuscular Disorders. October 2015 Oct 25:259-260.
Molecular Weight: 372.83
Research Area: Metabolic Disease
Target: Isotope-Labeled Compounds;Na+/H+ Exchanger (NHE)